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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZAP70 All Species: 12.73
Human Site: T276 Identified Species: 25.45
UniProt: P43403 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43403 NP_001070.2 619 69872 T276 T L P A H P S T L T H P Q R R
Chimpanzee Pan troglodytes XP_515637 619 69840 T276 T L P A H P S T L T H P Q R R
Rhesus Macaque Macaca mulatta XP_001101570 619 69877 T276 T L P A H P S T F T H P Q R R
Dog Lupus familis XP_861301 601 68596 S280 L S P P S R G S R P E S S F N
Cat Felis silvestris
Mouse Mus musculus P43404 618 70040 T276 P A H P S T F T Q P Q R R V D
Rat Rattus norvegicus Q64725 629 71510 P280 A H P V T W S P G G I I S R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515271 507 56102 I232 A P Q V E K L I A T T A H E R
Chicken Gallus gallus Q07494 984 109166 T488 S S V A R S Q T N T A R L E G
Frog Xenopus laevis Q91736 902 100832 S410 R S Q T N T A S I E G L R P G
Zebra Danio Brachydanio rerio O13146 981 109636 F565 L V L L V A C F I V S G R R C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24145 939 104255 G592 A G Q W I G N G Y Q P T M D V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189062 746 84636 D324 G S Q S I H V D D V H E Y D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 53.6 N.A. 93.5 53.7 N.A. 57.6 22.6 24.2 25.2 N.A. 25.1 N.A. N.A. 34
Protein Similarity: 100 100 98.3 70.4 N.A. 96.1 70.9 N.A. 62.6 35.5 39.1 37.4 N.A. 40.8 N.A. N.A. 49.4
P-Site Identity: 100 100 93.3 6.6 N.A. 6.6 20 N.A. 13.3 20 0 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 13.3 N.A. 13.3 20 N.A. 13.3 26.6 33.3 26.6 N.A. 6.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 0 34 0 9 9 0 9 0 9 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 9 9 0 0 0 0 17 9 % D
% Glu: 0 0 0 0 9 0 0 0 0 9 9 9 0 17 0 % E
% Phe: 0 0 0 0 0 0 9 9 9 0 0 0 0 9 0 % F
% Gly: 9 9 0 0 0 9 9 9 9 9 9 9 0 0 17 % G
% His: 0 9 9 0 25 9 0 0 0 0 34 0 9 0 0 % H
% Ile: 0 0 0 0 17 0 0 9 17 0 9 9 0 0 9 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 25 9 9 0 0 9 0 17 0 0 9 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 9 0 9 0 9 0 0 0 0 0 9 % N
% Pro: 9 9 42 17 0 25 0 9 0 17 9 25 0 9 0 % P
% Gln: 0 0 34 0 0 0 9 0 9 9 9 0 25 0 0 % Q
% Arg: 9 0 0 0 9 9 0 0 9 0 0 17 25 42 34 % R
% Ser: 9 34 0 9 17 9 34 17 0 0 9 9 17 0 0 % S
% Thr: 25 0 0 9 9 17 0 42 0 42 9 9 0 0 0 % T
% Val: 0 9 9 17 9 0 9 0 0 17 0 0 0 9 9 % V
% Trp: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _